EMERGENCY services are currently dealing with a collision between a Volvo car and BMW motorbike on the A417 near Cirencester.
The crash happened in thick fog between Granny's Pump near Syde and Cowley just before 8am.
The motorcyclist, who comes from Froome in Somerset, is said to have suffered serious, but not life-threatening injuries, in the incident and is currently being attended to by paramedics.
It is not yet known whether anybody travelling in the car has been injured.
Police have been called to a number of other minor accidents on the A417 this morning, mainly on the single-carriageway stretch of road close to the Air Balloon roundabout.
There have also been reports of at least two collisions on the A40 near Northleach including one involving two lorries and a car.