A family from Yate that have been battling for a potentially life-saving drug for their daughter are hoping there will be a breakthrough in the near future.

Liz and Shane Brennan, from Yate, have three children, sons Oscar and Finley and a daughter Annabelle.

Annabelle is now four-years-old and has Cystic Fibrosis.

She is one of around 10,500 people that have the condition in the UK alone, it affects nearly 100,000 people across the world.

Annabelle undergoes regular treatment for her condition, but her family are hoping that there will be a breakthrough in negotiations between NHS England and pharmaceutical company Vertex.

Vertex have produced a drug called Orkambi which has been scientifically proven to treat the root cause of Cystic Fibrosis rather than just the symptoms.

However the NHS and the pharmaceutical company can't come to an agreement over price.

Matt Hancock MP has previously stated that the government and NHS had made a 'record-breaking' offer to Vertex.

Liz has previously described living with Annabelle and her condition is like 'living on a knife edge'.

"I describe having a child with Cystic Fibrosis like living on the edge of a cliff. You just don't know what is going to happen over time.

"It is a complete unknown what could happen to her, Orkambi could stop the clock and delay any issues that may arise."

Liz went to London on Monday to campaign for Orkambi and reveals she welcomes talk of a potential breakthrough from current Health Minister Seema Kennedy MP.

"We are really pleased by this type of language by the government," she continued.

"Four years has been too long, the nature of this condition is that it doesn't wait and we have lost young people and many have now irreversible damage to their health.

"It is now quite right that the government puts the sufferers at the heart of this matter and gets these important medicines to children like our daughter in the fastest and safest way possible."